Biochemistry Den: 2010

Monday, April 26, 2010

Lecture video on NUCLEIC ACIDS - 1

Lecture Series on BioChemistry I by Prof.S.Dasgupta, Dept of Chemistry, IIT Kharagpur. For more details on NPTEl visit http://nptel.iitm.ac.in

Saturday, April 10, 2010

Few Important Animations

Tuesday, March 30, 2010

Andhra University M.Phil./Ph.D. RESEARCH ADMISSIONS - 2010

M.Phil./Ph.D. RESEARCH ADMISSIONS – 2010

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M.Phil./Ph.D. RESEARCH ADMISSIONS NOTIFICATION - 2010

RESEARCH COMMON ENTRANCE TEST AURCET-2010 (BROCHURE)

APPLICATION FORM FOR FULL-TIME M.PHIL./Ph.D. RESEARCH ADMISSION

APPLICATION FORM FOR PART-TIME M.PHIL./Ph.D. RESEARCH ADMISSION

Hall Ticket for Full Time AURCET - 2010

AURCET - 2010 *Syllabus*

Monday, March 29, 2010

JNU Jaipur BSc/MSc/PhD Life Sciences Admissions 2010@Biochemistryden/ Biotech, Bioinformatics, Microbiology, Biochemistry

JAIPUR NATIONAL UNIVERSITY
Jaipur-Agra Byepass
Jagatpura
Jaipur-302025

SCHOOL OF LIFE SCIENCE ADMISSIONS-2010

Applications are invited for admission to the following courses in Life Sciences:

S.No. - Course - Course Duration - Eligibility

i B.Sc. Pass Course (PCB + PCM) 3 Yrs. 10 + 2 in any stream of Science with minimum 50% (Maths / Biology ) i

i BSc Biotechnology (Integrated) 3 Yrs.

iii B.Sc. - MBA (Dual Degree) 4½ Yrs.

iv BSc-M.Sc. Integrated Biotechnology 3 + 2 Yrs.

v BSc-M.Sc. Integrated Microbial Technology 3 + 2 Yrs.

vi BSc-M.Sc. Integrated Bioinformatics 3 + 2 Yrs.

vii MSc Biotechnology 2 Yrs Minimum 55% aggregate in Graduation from any stream of Life Sciences

viii MSc Microbiology 2 Yrs

ix MSc Biochemistry 2 Yrs

x MSc Bioinformatics 2 Yrs

xi MSc + MBA (Dual Degree) 3½ Yrs.

xii MSc Biotechnology (Integrated) 2 Yrs Minimum 55% aggregate in B.Sc. Integrated Biotechnology or Honours Biotechnology

xiii Advanced PG Diploma in Clinical Research Management (Full-time) 1 Yr. Graduation or Postgraduation in Life Sciences / Microbiology / Biotechnology / Pharmacy / Medicine / Nursing / Physiotherapy / Dentistry / Homeopathy / Ayurvedic / Veterinary Science

xiv PG Diploma in Clinical Research (Part-time) 1 Yr.

xv MPhil in Life Sciences 1 Yr. Minimum 55% aggregate in Post Graduation from any stream of Life Sciences

xvi PhD in Life Sciences (Biotechnology/Microbiology/ Biochemistry Minimum 2 Yrs. Minimum 55% aggregate in Post Graduation from any stream of Life Sciences (preference will be given to M.Sc. in Biotechnology/Microbiology/Biochemistry/Life Sciences / Biosciences)

For admissions in Ph. D. programme, new guidelines of UGC will be followed.

The Application forms can be downloaded from http://jnujaipur.ac.in/index/

Last Date for Submission of Application Form: 30 APRIL 2010

APPLY ONLINE

Download Application form

Download Brochure

Mode of Admission

Ph: 0141-2753377, 9828119573 Fax: 2752418 E-mail: info@jnujaipur.ac.in, hareshmicrobiology@gmail.com

Request from JNU Jaipur

Friday, March 26, 2010

ICMR JRF 2010 | Fellowships for MSc Life Sciences

Indian Council of Medical Research (ICMR)
Ramalingaswami Bhawan, Ansari Nagar,
Post Box 4911, New Delhi-110029

Notification for ICMR's JRF - 2010

ICMR JRF Examination is the first step in the process of admission to the PhD/Research Programme through council's support. Test for ICMR JRF fellowship are conducted at the seven centres viz. Chandigarh, Chennai, Delhi, Kolkata, Hyderabad, Guwahati and Mumbai once a year. The award of JRF is made on merit basis by holding an entrance examination after issuing a countrywide admission notice. The admission notice is published in leading English Newspapers of India usually during March/April and also on the website. The entrance examination is usually held in the first/second week of July.

ICMR holds a national level examination for determining the eligibility of Indian National candidates for the award of Junior Research Fellowships (JRF) through Indian Council of Medical Research. The award of Junior Research Fellowship to the successful eligible candidates will depend on their finding placement in a medical college / hospital / university / national laboratory / institution of higher learning and research as applicable.

I. A total of 150 ICMR JRF Fellowships would be awarded. 120 JRF Fellowships would be awarded for work in the field of biomedical sciences with emphasis on Life Sciences (like microbiology, physiology, molecular biology, genetics, human biology, bioinformatics, biotechnology, biochemistry, biophysics, immunology, Pharmacology, zoology, Environment Science, botany, veterinary sciences, bio-informatics etc.). Thirty JRF Fellowships would be awarded for work with emphasis on Social sciences like psychology, sociology, home science, statistics, anthropology, social work and Health Economics.

(I-i) Two separate merit lists, one comprising the candidates qualifying for life sciences and the second for those candidates qualifying for social sciences, will be made on the basis of their performance in the above test.
(I-ii) The candidates selected for the JRF programme of ICMR would be permitted to enroll themselves for the Ph.D. programme of any University recognised by the UGC/MCI. However, the JRF programme would not have any connection with the Ph.D. programme. The validity of fellowship awarded to a candidate will be six months.

II. Another 100 candidates would be selected for consideration for positions of JRF under various research schemes of ICMR (subject to fulfilling the conditions for appointment under the schemes) for the duration of that scheme. These JRFs would also be permitted to complete Ph.D. while working in the scheme, if enrolled. The validity of result will be two years for placement in ICMR funded projects.

III. SC/ST/OBC/Physically Handicapped (PH) applicants will be given such special consideration as per policy guidelines.

Candidates qualifying for the award of JRF will receive fellowship from ICMR.

IV Duration and Emoluments for ICMR JRF 2010:

a. The existing value of the fellowship is at present Rs. 12000/- (Rupees Twelve thousand only) Per month. It will be revised from time to time as decided by the ICMR.
b. The duration of fellowship will initially be limited till three years carrying a monthly stipend of Rs. 12000/- and an annual contingency grant up to Rs. 20,000/- per annum. The progress of research work would be evaluated annually through annual progress reports. On completion of two years as JRF the stipend of a fellow may be increased to Rs. 14,000/- p.m. for 3rd year on the basis of assessment of candidate's research progress / achievements. Upon such a recommendation, the fellow will be called SRF. In the event of the Committee not recommending upgradation, the fellow will continue as JRF with a stipend of Rs. 12000/- per month for the 3rd year or his/her fellowship may be terminated depending on the decision of the Committee. The duration as SRF may be for a maximum duration of 3 years. Thus, the total tenure as JRF plus SRF shall not exceed 5 (five) years.

V The successful candidates would be notified by post and notice published in Employment Newspaper. The list also would be available on the ICMR website.

Joining time: Selected candidates must join their respective course on the prescribed date as indicated in their admission letter. The selection of those who fail to join by the specified date shall automatically stand cancelled.

Procedure for applying for ICMR JRF 2010

Before applying, candidates are advised to go through the admission notice published in the advertisement in various Newspapers and the instructions given therein carefully. Fill in the application form according to the instructions given in this prospectus and the admission notice. Incomplete applications will not be considered and no correspondence will be entertained.

Educational Qualification for ICMR JRF 2010:

M.Sc./M.A. or equivalent degree with minimum 55% marks for General/OBC Candidates and 50% for the SC/ST & physically handicapped candidates in the subjects mentioned under the head method of selection.

Age Limit

The age limit for admission to the eligibility test is 28 years (upper age limit relaxable upto 5 years in case of candidates belonging to SC/ST, physically handicapped (PH) and female candidates, 3 years in the case of OBC category.

Syllabus:

As prescribed by UGC.

Method of selection

Scheme of Test

The test will consist of one paper of 2 hours duration. The paper will consist of 2 Sections. The Aptitude Section (Section A) will have 50 questions on (i) scientific phenomenon in everyday life; (ii) general knowledge in sciences; and (iii) common statistics. All these questions would be compulsory with each question carrying 1 mark. The subject Specific Section (Section B & C) would pertain to (B) Life Sciences and (C) Social Science. The candidate may attempt questions in either of the two areas. Each area of section B & C would have 100 questions and the candidate may attempt any 75 questions in the predesigned area of Section B or C. Candidates are required to indicate the option for Section B or C in the application form too.

Each question carries one mark. Negative marking @ 0.25 will be made for each of the wrong answer. The questions in both the sections would appear in English only.

The final result will be based on aggregate of 55 % marks obtained in both the sections for General category and OBC and 50% for SC/ST and physically handicapped.

The test will be held in the following streams: (1) Aptitude test (common for all) (2) Life Sciences (3) Social Sciences. Subjects covered under Life Sciences include microbiology, physiology, molecular biology, genetics, human nutrition, human biology, biotechnology, biochemistry, biophysics, immunology, pharmacology, zoology, environmental sciences, botany, veterinary science and bio-informatics. Subjects covered under Social Sciences include psychology, sociology, home sciences, statistics, anthropology, social work and health economics..

Monitoring Mechanism: The fellow shall submit annual reports for 1^st year and annual report thereafter as per the prescribed standard proforma. The first annual report should be submitted after 10 months from the date of commencement of the fellowship (through the Guide along with his appraisal) giving complete factual details of the research work done. Subsequent annual reports as per the standard proforma should be submitted through the Guide two months before completion of the fellowship year

Advertisement for ICMR JRF 2010 | JRF Fellowships for MSc Life Sciences

See this notification also

What is the syllabus of CSIR UGCNET life science syllabus?

CSIR-UGC National Eligibility Test (NET) for

Junior Research Fellowship (JRF) and Lecturer-ship (LS)

SYLLABUS FOR LIFE SCIENCES

Just DOWNLOAD YOUR COPY with reference books in the syllabus

Download:CSIR UGC NET life science previouspaper Dec2008

CSIR UGC NET life science previous paper Dec2008

DOWNLOAD ur copy

Tuesday, March 23, 2010

Liver is an important organ in the human body

The liver is an important organ in the human body. Aside from creating functional molecules and chemicals for the body, it also removes compounds that could possibly poison other organs. Understanding the liver's functions will help prevent liver ailments by learning how to eat better to protect the liver and avoid disease

The Facts
The liver is the biggest organ in the human body. It is found in the right upper section of the abdomen and extends to the top of the diaphragm. The top part is beneath the right lung, the left end is under the heart, the left bottom side is above the stomach, and the right bottom side is above the gall bladder and right kidney and is protected by the right rib cage. Its color is reddish brown and it has a smooth texture. It has four lobes. The liver is larger when the human body is in its infancy stage and reduces in size as the body grows older. It weighs in at 1.2 to 1.5 kg in the female body and 1.3 to 1.6 kg in the male body.

Function:
The liver's function in the human body is to help break down and distribute nutrients in food. Medicine and alcohol are also processed by the liver so that toxins can be removed. The liver produces many chemical compounds that help in various bodily functions, some of which are to help blood to clot, maintain the glucose level in blood by breaking down and transforming glucose into glycogen, and regulating levels of amino acids, the building blocks of protein.

Significance:
The human body cannot function without the liver since it is responsible for many of the processes that the body needs to survive. One major function of the liver is to treat everything that is ingested and produced by the body and turn it into useful chemicals that aid other organs in maintaining the human body's functions. Byproducts that are not needed by the body are turned into waste and excreted.

Considerations
Medications and alcohol have a strong effect on the liver's health. A perfectly functioning liver means that all the organs in the human body will operate just as well. Alcohol abuse and prolonged intake of certain medications change the liver's metabolism and will affect its functions, possibly leading to liver diseases like cirrhosis, hepatitis, liver cancer or Wilson's disease.

Prevention
Drink plenty of fresh water throughout the day to help the liver do its job. Add more fruits and vegetables to your diet and give your liver a rest from red meats and processed food. Eat only fresh food and avoid food that has been reheated more than once. The liver weeds out any bacteria ingested through food intake, and too much harmful bacteria may cause liver damage. Avoid excessive intake of alcohol or avoid it altogether to prevent damage to the liver.

DOWNLOAD your copy

DOWNLOAD your copy

Thursday, March 18, 2010

Some Useful Downloads for CSIR-UGC-NET preparing students

· IIT JAM Previous Year Papers

· CSIR NET JRF Paper -2 Sample Question Paper (PDF format, 85 kb)

· IISc Entrance 2006 Question paper

· IISc Entrance 2008 Question Paper

· Download DBT JRF: Tips and tricks, how to prepare- class recording(16.39 MB, .exe format, requires adobe flash player)

· Download DBT JRF: Tips and Tricks, How to prepare Powerpoint(2.85 MB, PDF format)

· Download GATE Tips n Tricks eBook - Part 1

· CSIR NET JRF Subjective question Paper

· Special Class by Shikha Sinha: Part 2- 22nd march 2009

· Special Online Class on Molecular Biology Tools and Techniques - Class Recording - Conducted by Mrs Shikha Sinha for CSIR NET JRF Students ( 21.6 MB)

· GENETICALLY MODIFIED ORGANISMS ( GMOs) & ENVIRONMENT

· CANCER TREATMENT BY HUMANIZED ANTIBODY

source: biotecnika.org

Check your Life Science knowledge with this Test in CSIR-UGC-NET

Just Click “Click Here” link and give ur name & Email ID. this test help by biotecnika.org

Test 1
Generalised full syllabus test on all india basis
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Test 2
Generalised full syllabus test on all india Basis
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Test 3
Cell organisation,Chromosomes,DNA-structure and replication,Evolution, RDT and genetic engineering

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Test 4

Proteins-
- structure,
- classification &
- properties,
Carbohydrates,
Fat metabolism,
Nitrogen metabolism
Vitamins

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Test 5

Enzymes,Coenzymes (Activators,Inhibitors)
Thermodynamics
Enzyme Kinetics
Enzyme activity regulation
pH (H.H Equation)

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Test 6

Nucleic Acid Structure
Genetic code
DNA Repair
DNA replication
Transcription
Translation

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Test 7

Cell division
cell organelle
- structure
- Function
Cell cell Interaction
Structure of Prokaryotic and Eukaryotic cell

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Test 8

Bioenergetics,
glycolysis,
oxidative phosphorylation,
coupled reaction,
group transfer,
biological energy transducers

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Test 9

Amino Acid Metabolism
Cordinated control of metabolism
Biosynthesis of Purines & Pyrimidines
Oxidation of Lipids
Biosynthesis of Fatty acid, Triglyceride, Phospholipid and Sterol.

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Test 10
Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.
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Test 11
COMMON ELEMENTRY COMPUTER SCIENCE: dealing with basic computer awareness and uses
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Test 12

Principals and applications of Gel Filtration
Ion Exchange and affinity Chromatography
Thin layer and Gas chromatography
HPLC
Principals and applicationsNucleic Acid Hybridization and cot curve
Sequencieng of Proteins and nucleic acid
Southern, South-western, northern blotting
PCR

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ALL THE BEST

Source: biotecnika.org/net-jrf-coaching

Tuesday, March 16, 2010

How do NADP+ and NADPH differ from NAD+ and NADH?

These pairs of molecules are identical except for the presence of a phosphate group at the 2′ position on the ribose moiety. This is not a high-energy phosphate but rather a molecular tag that enables enzymes to discriminate between the two forms of redox compound. In higher animals there do not appear to be any NADH transferase enzymes that catalyze direct transfer of hydrogen atoms from NADH to NADP+ or from NADPH to NAD+.

NADH and NADPH are equivalent in terms of their standard redox potentials, but because redox enzymes are usuallyselective for one or the other of them, two distinct pools of reductants exist. NADH is used as a source of reducing equivalents for the electron transport chain (ETC) while NADPH provides reducing equivalents for many biosyntheticreactions. Hence, even within a single spatial compartment such as the cytoplasm, the NADH to NAD+ ratio can be very low, favoring oxidation of fuels, while simultaneously the NADPH to NADP+ ratio can be very high, facilitating biosynthesis.

Schaum's Outline of Immunology

Based on material from 400-600 level Immunology courses, this concise and thorough review of modern concepts in molecular, cellular, and systemic immunology contains over two hundred detailed problems with step-by-step solutions. Taking a problem-solving approach, Schaum's Outline of Immunology is an excellent supplement to any systematic textbook of modern immunology, focusing on the basic tenets of immunology as applied to the dynamics of immune responses and their outcomes, and is perfect for pre-med students who need help in their required immunology courses, as well asfor medical and veterinary students who want to update their knowledge

Monday, March 15, 2010

Immunology Notes for Students

Immunology
Immune System, Anatomy of the immune system,
Immunity Mediated by B Cells and Antibodies
Manipulation of the Immune Response
Innate Immune System, Innate Immunity, Innate Immunity2, Anatomical Barriers,
Mechanical Removal, Bacterial Antagonism, and Antigen-Nonspecific Antimicrobial Chemicals Produced by the body
Pattern-Recognition Receptors (Including Toll-Like Receptors) and Cytokines
Adaptive Immunity to Infection,
Cells of innate immune system
B Cells and T Cells: lymphocytes of the immune system, Regulatory T cells, T Helper cells, Cell-Mediated Immunity
lymphatic system and immunity,
Phagocytosis, The Process of Phagocytosis, Natural Killer (NK) Cells, Mast Cells, Basophils, Dendrite cells
Defense Cells in the Blood: The Leukocytes
Defense Cells in the Tissue: Macrophages, Dendritic Cells, and Mast Cells
Cytotoxic T lymphocytes (CTL)
Lymphocytes, Lymphoid organ
The Complement System, Complement System
Classical Complement Pathway, Lectin Pathway, Alternative Complement Pathway
How MO's Resist Body Defenses by Circumventing the Complement Pathways
Antigen, Antigen Presentation (how antigens are "presented" to B cells & T cells), Antigen Receptors (on B cells & T cells)
Antigen Receptor Diversity, Antigen recognition
Antibodies, Antibody affinity, Antibody-Antigen Binding, Antibody response
Cytokines
Regulation to the immune response
Autoimmunity and Transplantation
Transplantation, organ transplantation, bone marrow transplantation
Vaccination, Vaccines, Vaccines2, Passive Immunity
Immunotechnology, Monoclonal antibodies, ELISA (enzyme-linked immunosorbent assay), Radioimmunoassay, Cancer Immunotherapy
Immune disease and condition, AIDS, Allergies, immunology of Asthma, Autoimmunity and autoimmune disease, Infection, Immunodeficiency, ADA SCID,allergic asthma, anaphylaxis, aplastic anemia, arteritis, arthritis, Autoimmune lymphoproliferative syndrome, celiac disease, conjunctivitis, Crohn's disease,elephantiasis, Graves Disease, Guillain-Barre Syndrome, HIGM, IFN-γ receptor deficiency, leprosy, Lyme Disease, malaria, MCL, mononucleosis, Omenn's syndrome, psoriasis, rabies, scleroderma, systemic lupus erythemtosus, Trypanosomiasis, Wiskott-Aldrich Syndrome, Autoimmune Polyglandular Syndrome,Rheumatic Fever, Fever
Activation-induced Cytidine Deaminase (AID) Deficiency, Immune Tolerance
Hypersensitivity Inflammation, Inflammation2
Nutritional Immunity
The Acute Phase Response
Clonal selection and immunological memory
Games Parasites Play: some ways of evading the immune responses of their host
Histocompatibility Molecules: and their role in eliciting an immune response
HLA-A2: the structure of a class I histocompatibility molecule
The Immunological Synapse
Nude Mice
Immune Proteins
B7s, C3, C5, CAD, CD1, CD3, CD40L, CD45, CD59, CTLA-4, DAF, E and P selectin, FAS, HLA-DM, INF-γ, Lck, MBL, MIF, NFAT, NFκB, pTa,RAG1-2, TAP, tapasin, TdT, TLR-2, ZAP-70,

Glossary